[Frontiers in Bioscience 8, s140-148, January 1, 2003] 140 MHC RESTRICTION IN ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS

1. Abstract 2. Introduction 3. MHC Class I and II Molecules 3.1. Function of MHC Class I and Class II molecules 3.2. Structure of MHC Class I and Class II molecules 3.3. Antigen binding by MHC Class I and Class II molecules 3.4. MHC polymorphism on peptide binding 3.5. Antigen presentation by MHC Class II molecules 4. MHC and disease associations 4.1. Associations between MHC polymorphism and disease 4.2. Allergic responses and HLA 5. HLA class II restriction specificity of T cell recognition in ABPA 5.1. HLA-DRB1 allele distribution among ABPA, non-ABPA, and normal controls 5.2. HLA-DQ specificities in ABPA, non-ABPA and normal controls 6. Conclusion 7. Acknowledgments 8. References